Papers

2023

Plant-based production of a protective vaccine antigen against the bovine parasitic nematode Ostertagia ostertagi Zwanenburg, L; Borloo, J; Decorte, B; Bunte, MJM; Mokhtari, S; Serna, S; Reichardt, N; Seys, LJM; van Diepen, A; Schots, A; Wilbers, RHP; Hokke, CH; Claerebout, E; Geldhof, P Scientific Reports, 13, (20488)  DOI:10.1038/s41598-023-47480-3, 2023

Structural insights into a cooperative switch between one and two FimH bacterial adhesins binding pauci-and high-mannose type N-glycan receptors. Krammer, E.M., Bridot, C., Serna, S., Echeverria, B., Semwal, S., Roubinet, B., van Noort, K., Wilbers, R.H., Bourenkov, G., de Ruyck, J. and Landemarre, L., Journal of Biological Chemistry, 299(5), 2023.

Versatile Urea Type Linker For The Functionalisation of Natural Glycans and its Validation in Glycan Arrays Serna, S; Artschwager, R; Pérez-Martínez, D; Lopez, R; Reichardt, N. A Chemistry–A European Journal 29, no. 52, 2023

    2022

    Cross-reactivity of glycan-reactive HIV-1 broadly neutralizing antibodies with parasite glycans, Huettner, I., Krumm, S. A., Serna, S., Brzezicka, K., Monaco, S., Walpole, S., … & Doores, K. J. (2022). Cell Reports, 38(13), 110611.

    Immobilization of Biantennary N-Glycans Leads to Branch Specific Epitope Recognition by LSECtin, Bertuzzi, S; Peccati, F; Serna, S; Artschwager, R; Notova, S; Thépaut, M; Jiménez-Osés, G; Fieschi, F; Reichardt, NC; Jiménez-Barbero, J; Ardá, A., ACS Central Science 2022, , ()  DOI:10.1021/acscentsci.2c00719

    A galactoside-specific Dalbergieae legume lectin from seeds of Vataireopsis araroba (Aguiar) Ducke. Osterne, V. J., Oliveira, M. V., De Schutter, K., Serna, S., Reichardt, N. C., Smagghe, G., … & Nascimento, K. S. (2022). Glycoconjugate Journal, 1-11.

    N-Glycans in Immortalized Mesenchymal Stromal Cell-Derived Extracellular Vesicles Are Critical for EV-Cell Interaction and Functional Activation of Endothelial Cells, Clos-Sansalvador, M; Garcia, SG; Morón-Font, M; Williams, C; Reichardt, N; Falcón-Pérez, JM; Bayes-Genis, A; Roura, S; Franquesa, M; Monguió-Tortajada, M; Borràs, FE., International Journal of Molecular Sciences, 2022, 23, (9539)  DOI:10.3390/ijms23179539 IF: 5.923, Q1, d3

    COVID-BIOCHIP: A Web Tool to Analyse COVID-19 Antigen Microarrays, Sucre, A; Amaya-Rodriguez, I; Rho, H; Serna, S; Reichardt, N; Garin-Muga, A; Epelde, G., Studies in Health Technology and Informatics 2022, , ()  DOI:10.3233/SHTI220692

    2021

    Controlled Density Glycodendron Microarrays for Studying Carbohydrate-Lectin Interactions, Antonio Di Maio, Anna Cioce, Silvia Achilli, Michel Thépaut , Corinne Vivès, Franck Fieschi, Javier Rojo, Niels-C. Reichardt, OBC, 2021 in press

    FUT8-directed core fucosylation of N-glycans is regulated by the glycan structure and protein environment, García-García, Ana; Serna, Sonia; Yang, Zhang; Delso, Ignacio; Taleb, Victor; Hicks, Thomas; Artschwager, Raik; Vakhrushev, Sergey; Clausen, Henrik; Angulo, Jesus  ; Corzana, Francisco; Reichardt, Niels-Christian; Hurtado-Guerrero, Ramon, ACS Catalysis, 2021, in press

    Minimal epitope for Mannitou IgM on paucimannose-carrying glycoproteins, Stefania Robakiewicz, Clarisse Bridot, Sonia Serna, Ana Gimeno, Begoña Echeverria, Sandra Delgado, Jérôme de Ruyck, Shubham Semwal, Diego Charro, Ann Dansercoer, Kenneth Verstraete, Mikel Azkargorta, Kim van Noort, Ruud Wilbers, Savvas N. Savvides, Nicola G. A. Abrescia, Ana Arda, Niels C. Reichardt*, Jesús Jiménez-Barbero*  and Julie Bouckaert*, Glycobiology, 2021, accepted proof

    Longitudinal Development of Antibody Responses in COVID-19 Patients of Different Severity with ELISA, Peptide and Glycan Arrays: An Immunological Case Series, Jasmin Heidepriem, Christine Dahlke, Robin Kobbe , René Santer, Till Koch, Anahita Fathi, Bruna M. S. Seco, My L. Ly, Stefan Schmiedel, Dorothee Schwinge, Sonia Serna, Katrin Sellrie, Niels-Christian Reichardt, Peter H. Seeberger, Marylyn M. Addo, Felix F. Loeffler and on behalf of the ID-UKE COVID-19 Study Group, Pathogens 2021, 10, 438, https://doi.org/10.3390/pathogens10040438

    2020

    The interaction of fluorinated glycomimetics with DC-SIGN: multiple binding modes disentangled by the combination of NMR methods and MD simulations, J. Daniel Martinez, Angela S. Infantino, Pablo Valverde, Tammo Diercks, Sandra Delgado, Niels-Christian Reichardt, Ana Arda, Francisco Javier Cañada, Stefan Oscarson, Jesus Jimenez-Barbero, Pharmaceuticals 2020, 13(8), 179; https://doi.org/10.3390/ph13080179

    TETRALEC, Artificial Tetrameric Lectins: a tool to screen ligand and pathogen interactions, Silvia Achilli, João T. Monteiro, Sonia Serna, Sabine Mayer-Lambertz, Michel Thépaut, Aline Le Roy, Christine Ebel, Niels-Christian Reichardt, Bernd Lepenies, Franck Fieschi, Corinne Vivès, Int. J. Mol. Sci. 2020, 21(15), 5290;

    Cross-reactive carbohydrate determinant-specific IgE obscures true atopy and exhibits selective inverse associations with asthma, Gyaviira Nkurunungi, Harriet Mpairwe, Serge A Versteeg, Angela van Diepen, Jacent Nassuuna, Joyce Kabagenyi, Irene Nambuya, Richard E Sanya, Margaret Nampijja, Sonia Serna, Niels-Christian Reichardt, Cornelis H Hokke, Emily L Webb, Ronald van Ree, Maria Yazdanbakhsh, Alison M Elliott, Allergy, 2020, Volume76, Issue1, January 2021, Pages 233-246, DOI 10.1111/all.14469

    Fluorinated carbohydrates as chemical probes for molecular recognition studies. Current status and perspectives, Bruno Linclau, Ana Ardá, Niels-Christian Reichardt, Matthieu Sollogoub, Luca Unione, Stéphane P. Vincent and  Jesús Jiménez-Barbero, Chemical Society Reviews, 2020, 49, 3863 – 3888

    Chemo-enzymatic Synthesis of S.mansoni O-glycans and their Evaluation as Ligands for C-type Lectin Receptors MGL, DC-SIGN and DC-SIGNR Julie Pham, Alvaro Hernandez, Anna Cioce, Silvia Achilli, Giulio Goti, Corinne Vivès, Michel Thepaut, Anna Bernardi, Franck Fieschi, Niels-Christian Reichardt, Chem. Eur. J. 2020, 6;26(56):12818-12830. doi: 10.1002/chem.202000291.

    Rapid On‐chip Synthesis of Complex Glycomimetics from N‐glycan Scaffolds for Improved Lectin Targeting, Anna Cioce, Michel Thépaut, Franck Fieschi, Niels-Christian Reichardt, Chem. Eur. J., 2020, 6;26(56):12809-12817. doi: 10.1002/chem.202000026.

    Structural basis for substrate specificity and catalysis of α1,6-fucosyltransferase
    Ana García-García, Laura Ceballos-Laita, Sonia Serna, Raik Artschwager, Niels C. Reichardt, Francisco Corzana, Ramon Hurtado-Guerrero, Nature Communications, 11, Article number: 973 (2020)

    2019

    Mass Spectrometry of Carbohydrate-Protein Interactions on a Glycan Array Conjugated to CVD Graphene Surfaces Juan Pedro Merino, Sonia Serna, Alejandro Criado, Alba Centeno, Ilargi Napal, Javier Calvo, Amaia Zurutuza, Niels Reichardt and Maurizio Prato, 2D Materials, 2019, 7(2), 0240039

    Metabolomics analysis of extracellular vesicles, review, Charles Williams, Mari Palviainen, Niels-Christian Reichardt, Pia Siljander, Juan Manuel Falcón-Pérez,  Metabolites, 2019, 9(11), 276; https://doi.org/10.3390/metabo9110276

    NIST Interlaboratory Study on Glycosylation Analysis of Monoclonal Antibodies: Comparison of Results from Diverse Analytical Methods, Maria Lorna A. De Leoz , David L. Duewer, Adam Fung, Lily Liu, Hoi Kei Yau, Oscar Potter, Gregory O. Staples, Kenichiro Furuki, Ruth Frenkel, Yunli Hu, Zoran Sosic, Peiqing Zhang, View ORCID ProfileFriedrich Altmann, Clemens Gruber, Chun Shao, ProfileJoseph Zaia, Waltraud Evers, Stuart Pangelley, Detlev Suckau, Anja Wiechmann, Anja Resemann, Wolfgang Jabs, Alain Beck, John W Froehlich, ChunCui Huang, Yan Li, YaMing Liu, Shiwei Sun, Yaojun Wang, Youngsuk Seo, Hyun Joo An, Niels-Christian Reichardt, Juan Echevarria Ruiz, Stephanie Archer‑Hartmann, Parastoo Azadi, Len Bell, Zsuzsanna Lakos, Yanming An, John F Cipollo, Maja Pučić-Baković, Jerko Štambuk, Gordan Lauc, Xu Li,Peng George Wang, Andreas Bock, René Hennig, Erdmann Rapp, Marybeth Creskey, Terry Cyr, Miyako Nakano, Taiki Sugiyama, Pui‑King Amy Leung, Paweł Link‑Lenczowski, Jolanta Jaworek, Shuang Jake Yang, Hui Zhang, Tim Kelly, Song Klapoetke, Rui Cao, Jin Young Kim, Hyun Kyung Lee, Juyeon Lee, Jong Shin Yoo, Sa‑Rang Kim, Soo‑Kyung Suh, Noortje de Haan, David Falck, Guinevere S.M. Lageveen-Kammeijer, Manfred Wuhrer, Robert J. Emery, Radoslaw P. Kozak, Li Phing Liew, Louise Royle, Paulina A. Urbanowicz, Nicolle Packer, Xiaomin Song, Arun Everest-Dass, Erika Lattová, Samanta Cajic, Kathirvel Alagesan, Daniel Kolarich, Toyin Kasali, Viv Lindo, Yuetian Chen, Kudrat Goswami, Brian Gau, Ravi Amunugama, Richard Jones, Corné J. M. Stroop, Koichi Kato, Hirokazu Yagi, Sachiko Kondo, CT Yuen, Akira Harazono, Xiaofeng Shi, Paula Magnelli, Brian T Kasper, Lara K. Mahal, David J. Harvey, Roisin Majella O’Flaherty, Pauline Rudd, Radka Saldova, Elizabeth S. Hecht, David C. Muddiman, Jichao Kang, Prachi Bhoskar, Daniele Menard, Andrew Saati, Christine Merle, Steven Mast, Sam Tep, Jennie Truong, Takashi Nishikaze, Sadanori Sekiya, Aaron Shafer, Sohei Funaoka, Masaaki Toyoda, Peter de Vreugd, Cassie Caron, Pralima Pradhan, Niclas Chiang Tan, Yehia Mechref, Sachin Patil, Jeffrey S. Rohrer, Ranjan Chakrabarti, Disha Dadke, Mohammedazam Lahori, Chunxia Zou, auren D. Wu, Andras Guttman, Marton Szigeti, Benjamin G. Kremkow, Kelvin Lee, Carina Sihlbom, Barbara Adamczyk, Chunsheng Jin, Niclas G. Karlsson, Jessica Örnros, Göran Larson, Jonas Nilsson, Bernd Meyer, Alena Wiegandt, Emy Komatsu, Helene Perreault, Edward D Bodnar, Nassur Said, Yannis‑Nicolas Francois, Emmanuelle Leize-Wagner, Sandra Maier, Anne Zeck, Albert J. R. Heck, Yang Yang, Rob Haselberg, Ying Qing Yu, William Alley, Joseph W. Leone, Hua Yuan and Stephen E. Stein, Molecular & Cellular Proteomics October 7, 2019, mcp.RA119.001677;

     Assessing the role of surface glycans of extracellular vesicles on cellular uptake Charles Williams, Raquel Pazos, Félix Royo, Esperanza González, Meritxell Roura-Ferrer, Aitor Martinez, Jorge Gamiz, Niels‑Christian Reichardt and Juan M Falcón-Pérez, Scientific Reports, 9, Article number: 11920 (2019)

    Molecular insights into DC-SIGN binding to self-antigens: the interaction with the blood group A/B antigens Valverde, Pablo; Delgado, Sandra; Martinez, J. Daniel; Vendeville, Jean-Baptiste ; Malassis, Julien; Linclau, Bruno; Reichardt, Niels-Christian; Cañada, Francisco; Jiménez-Barbero, Jesús; Arda, Ana ACS Chem. Biol. 2019, 147, 1660-1671

    Glycans in Drug Discovery Valverde, Pablo; Ardá, Ana; Reichardt, Niels-Christian; Jimenez-Barbero, Jesus; Gimeno, Ana Med. Chem. Commun., 2019,10, 1678-1691

    Unraveling novel sugar binding modes to DC-SIGN by employing
    fluorinated carbohydrates J. Daniel Martinez, Pablo Valverde, Sandra Delgado, Cecilia Romano, Bruno Linclau, Niels C. Reichardt, Stefan Oscarson, Ana Arda, Jesus Jimenez-Barbero, F. Javier Cañada, Molecules 2019, 24(12), 2337;

    Microarray assessment of N-glycan-specific IgE and IgG profiles associated with Schistosoma mansoni infection in rural and urban Uganda Gyaviira Nkurunungi, Angela van Diepen, Jacent Nassuuna, Richard E Sanya, Margaret Nampijja, Irene Nambuya, Joyce Kabagenyi, Sonia Serna, Niels-Christian Reichardt, Ronald van Ree, Emily L Webb, Alison M Elliott, Cornelis H Hokke, Maria Yazdanbakhsh, Scientific Reports, 2019 volume 9, Article number: 3522 (2019)

    2018

    Fluorescent Neoglycoprotein Gold Nanoclusters: Synthesis and Applications in Plant Lectin Sensing and Cell Imaging Brzezicka, K.A., Serna, S. & Reichardt, N.C. Nanoscale Res Lett 13, 360 (2018). https://doi.org/10.1186/s11671-018-2772-2

    Measuring bacterial glycosyl hydrolase activity with a soluble capture probe by mass spectrometry, Sonia Serna, María Ercibengoa, Jose María Marimón, Niels-Christian Reichardt*, Analytical Chemistry, 2018, DOI: 10.1021/acs.analchem.8b02434

    Glycan Microarray-Assisted Identification of IgG Subclass targets in Schistosmiasis, Y. Y. Michelle Yang, Angela van Diepen, Katarzyna Brzezicka, Niels-Christian Reichardt and Cornelis H. Hokke, Frontiers in Immunology, 2018, doi.org/10.3389/fimmu.2018.02331

    On-chip screening of a glycomimetic library with C-type lectins reveals structural features responsible for preferential binding of dectin-2 over DC-SIGN/R and langerinLaura Medve, Silvia Achilli, Sonia Serna, Fabio Zuccotto, Norbert Varga, Michel Thépaut, Monica Civera, Corinne Vivès, Franck Fieschi, Niels Reichardt, and Anna Bernardi, Chemistry-A European Journal, 2018, https://doi.org/10.1002/chem.201802577

    Chemoenzymatic Synthesis of N-glycan Positional Isomers and Evidence for Branch Selective Binding by Monoclonal Antibodies and Human C-type Lectin Receptors, B. Echeverria, S. Serna, S. Achilli, C. Vivès, J. Pham, M. Thépaut, C. H. Hokke, F. Fieschi, N.-C. Reichardt, ACS Chem. Bio., 2018, 10.1021/acschembio.8b0043

    Mass spectrometry for glycan biomarker discovery, O. Aizpurua-Olaizola, J. Sastre Toraño, J.M. Falcon-Perez, C. Williams, N. Reichardt, G.-J. Boons, TrAC Trends in Analytical Chemistry, Volume 100, March 2018, Pages 7-14

    Glycosylation Of Extracellular Vesicles: Current Knowledge, Tools And Clinical Perspectives, Charles Williams, Felix Royo, Oier Aizpurua-Olaizola, Raquel Pazos, Geert-Jan Boons, Niels-Christian Reichardt and Juan M Falcon-Perez, J. Extracell. Vesicles 2018; 7(1): 1442985.

    Identification of dominant anti-glycan IgE responses in school-children by glycan microarrayAbena S. Amoah, Elias K. Asuming-Brempong, Benedicta B. Obeng, Serge A. Versteeg, Irene A. Larbi, Yvonne Aryeetey, Thomas A.E. Platts-Mills, Adriano Mari, Katarzyna Brzezicka, Ben A. Gyan, Mohamed Mutocheluh, Daniel A. Boakye, Niels-Christian Reichardt, Ronald van Ree, Cornelis H. Hokke, Angela van Diepen, Maria Yazdanbakhsh,  J. Allergy Clin. Immunol. 2018, Volume 141, Issue 3, Pages 1130–1133 

    2017

    Analysis of Defective Protein Ubiquitylation Associated to Adriamycin Resistant Cells Valérie Lang, Fabienne Aillet, Wendy Xolalpa, Sonia Serna, Laurie Ceccato, Rosa G. Lopez-Reyes, Maria Paz Lopez-Mato, Radosław Januchowski, Niels- Christian Reichardt, Manuel S. Rodriguez, Cell Cycle, 2017, early view online version

    Lectin-Array Blotting, Raquel Pazos, Juan Echevarria, Alvaro Hernandez, Niels-Christian Reichardt, Curr. Protocols in Cell Biol. 2017, DOI: 10.1002/cpcb.20

    NMR and Molecular Recognition of N-Glycans: Remote Modifications of the Saccharide Chain Modulate Binding Features,  Ana Gimeno, Niels-Christian Reichardt, Francisco Javier Cañada, Lukas Perkams, Carlo Unverzagt, Jesus Jimenez-Barbero, and Ana Arda,  ACS Chem. Biol., 2017, 12 (4), pp 1104–1112

    Specific anti-glycan antibodies are sustained during and after parasite clearance in Schistosoma japonicum-infected rhesus macaques Y.Y. Michelle Yang, Xiao Hong Li, Katarzyna Brzezicka, Niels-Christian Reichardt, R. Alan Wilson, Angela van Diepen and Cornelis H. Hokke,  PLoS Neglected Tropical Diseases (2017), http://dx.doi.org/10.1371/journal.pntd.0005339

    Fluoroacetamide Moieties as NMR Probes for molecular recognition of GlcNAc-containing sugars: Modulation of the CH-π Stacking Interactions by Different Fluorination Patterns, Luca Unione, Maria Alcalá, Begoña Echeverria, Sonia Serna, Ana Ardá, Antonio Franconetti, F. Javier Cañada, Tammo Diercks, Niels Reichardt, Jesús Jiménez-Barbero, Chemistry,-Eur. J. .2017, DOI: 10.1002/chem.201605573

    2016

    Carbohydrate-Binding Non-Peptidic Pradimicins for the Treatment of Acute Sleeping Sickness in Murine Models, Castillo-Acosta VM, Ruiz-Pérez LM, Etxebarria J, Reichardt NC, Navarro M, Igarashi Y, et al. (2016)  PLoS Pathog 12(9): e1005851. DOI:10.1371/journal.ppat.1005851

    Opportunities for Glyconanomaterials in Personalized Medicine, Reichardt, N.-C.; Martin-Lomas, M. ; Penades, S.; Chem. Commun., 2016, 52, 13430 – 13439

    Efficient monitoring of protein ubiquitylation levels using TUBEs-based microarraysSerna, S., Xolalpa, W., Lang, V., Aillet, F., England, P., Reichardt, N., & Rodriguez, M. S.  FEBS letters, 2016,  590,(16), 2748–2756

    Influence of Core β-1,2-xylosylation on Glycoprotein Recognition by Murine C-type Lectin Receptors and its Impact on Dendritic Cell Targeting; Brzezicka K.;  Vogel U., Serna S., Johannssen T., Lepenies B.,  Reichardt N.C., ACS Chem. Biol., 2016, 11 (8), pp 2347–2356

    Methods for the absolute quantification of N-glycan biomarkers. Etxebarria J. and Reichardt N.C.; Biochim. Biophys Acta, 1860,8, 1676–1687 (2016)

    2015

    Chemo-Enzymatic Synthesis of 13C Labeled Complex N-Glycans As Internal Standards for the Absolute Glycan Quantification by Mass Spectrometry. Echeverria B., Etxebarria J., Ruiz N., Hernandez A., Calvo J., Haberger M, Reusch D. and Reichardt N.C.; Anal. Chem. , 87 (22), 11460–11467 (2015)

    On the molecular interaction between albumin and ibuprofen: an AFM and QCM-D study. Eleta-Lopez A., Etxebarria J., Reichardt N., Georgieva R., Bäumler H. and Toca-Herrera J.L.; Colloid Surface. B 134, 355-362 (2015).

    Monitoring Glycan-Protein Interactions by NMR Spectroscopic Analysis: A Simple Chemical Tag That Mimics Natural CH-π Interactions. Calle L.P., Echeverría B., Franconetti A., Serna S., Fernández-Alonso M.C., Diercks T., Cañada J., Ardá A., Reichardt N.C. and Jiménez-Barbero J.; Chem. Eur. J., 21, 11408–11416 (2015).

    Algal lectin binding to core (α1-6) fucosylated N-glycans: Structural basis for specificity and production of recombinant protein. Do Nascimento A.S.F., Serna S., Beloqui A., Arda A., Sampaio A.H., Walcher J., Ott D., Unverzagt C., Reichardt N.C., Jimenez-Barbero J., Nascimento K.S., Imberty A., Cavada B.S. and Varrot A.; Glycobiology 25, 607 – 616 (2015).

    Synthesis and Microarray-Assisted Binding Studies of Core Xylose and Fucose Containing N-Glycans. Brzezicka K., Echeverria B., Serna S.,Van Diepen A., Hokke C.H. and Reichardt N.C.; ACS Chem. Biol. 10, 1290 – 1302 (2015).

    Solid-phase assembly of glycosaminoglycan oligosaccharide precursors. Guedes N., Kopitzki S., Echeverría B., Pazos R., Elosegui E., Calvo J. and Reichardt N.C.; RSC Adv. 5, 9325 – 9327 (2015).

    Nanostructured Indium Tin Oxide Slides for Small-Molecule Profiling and Imaging Mass Spectrometry of Metabolites by Surface-Assisted Laser Desorption Ionization MS. Lopez de Laorden C., Beloqui A., Yate L., Calvo J., Puigivila M., Llop J. and Reichardt N.C.; Anal. Chem. 87, 431-440 (2015).

    2014

    Importance of the polarity of the glycosaminoglycan chain on the interaction with FGF-1. Muñoz-García J.C., García-Jiménez M.J., Carrero P., Canales A., Jiménez-Barbero J., Martín-Lomas M., Imberty A., de Paz J. L., Angulo J., Lortat-Jacob H. and Nieto P.M.; Glycobiology 24, 1004-1009 (2014).

    Microarray-Based Identification of Lectins for the Purification of Human Urinary Extracellular Vesicles Directly from Urine Samples. Echevarria J., Royo F., Pazos R., Salazar L., Falcon-Perez J.M. and Reichardt N.C.; ChemBioChem 15, 1621 – 1626 (2014).

    Cross-platform comparison of glycan microarray formats. Wang L., Cummings R.D., Smith D.F., Huflejt M., Campbell C.T. Gildersleeve J.C. Gerlach J.Q., Kilcoyne M., Joshi L., Serna S., Reichardt N.C., Parera Pera N., Pieters R.J., Eng W. and Mahal L.K.; Glycobiology 24, 507 – 517 (2014).

    Nanostructured weathering steel for matrix-free laser desorption ionisation mass spectrometry and imaging of metabolites, drugs and complex glycans. Etxebarria J., Calvo J. and Reichardt N.C.; Analyst 139, 2873 – 2883 (2014).

    Biological Evaluation of Multivalent Lewis X-MGL-1 Interactions. Eriksson M., Serna S., Maglinao M., Schlegel M.K., Seeberger P.H., Reichardt N.C. and Lepenies B.; ChemBioChem 15, 844 – 851 (2014).

    2013

    Heparin Modulates the Mitogenic Activity of Fibroblast Growth Factor by Inducing Dimerization of its Receptor. A 3D View by Using NMR. Nieto L., Canales A., Fernández I.S., Santillana E., González-Corrochano R., Redondo-Horcajo M., Cañada F.J., Nieto P., Martín-Lomas M., Giménez-Gallego G. and Jiménez-Barbero J.; ChemBioChem 14, 1732-1744 (2013).

    Towards the Solid-Phase Synthesis of Heparan Sulfate Oligosaccharides: Evaluation of Iduronic Acid and Idose Building Blocks. Guedes N., Czechura P., Echeverria B., Ruiz A., Michelena O., Martin-Lomas M. and Reichardt N.C.; J. Org. Chem. 78, 6911-6934 (2013).

    Array-assisted characterisation of a fucosyltransferase required for the biosynthesis of complex core modifications of nematode N-glycans. Yan S., Serna S., Reichardt N.C, Paschinger K. and Wilson I. B. H.; J. Biol. Chem 288, 21015-21028 (2013).

    Analysis of Microarrays by MALDI-TOF MS. Beloqui A., Calvo J., Serna S., Yan S., Wilson I. B. H, Martin-Lomas M. and Reichardt N.C.; Angew. Chem. Int. Ed. 52, 7477 -7481 (2013).

    Glyconanotechnology. Reichardt N.C., Martín-Lomas M. and Penadés S.; Chem. Soc. Rev. 42, 4358-4376 (2013).

    Profiling Glycosyltransferase Activities by Tritium Imaging of Glycan Microarrays . Serna S., Hokke C.H., Weissenborn M., Flitsch S., Martin-Lomas M. and Reichardt N.C.; ChemBioChem 14, 862-869 (2013).

    Three-Dimensional Arrays Using GlycoPEG Tags: Glycan Synthesis, Purification and Immobilisation. Etxebarria J., Serna S., Beloqui A., Martin-Lomas M. and Reichardt N.C.; Chem. Eur. J. 19, 4776-4785 (2013).

    2012

    Effect of the Substituents of the Neighboring Ring in the Conformational Equilibrium of Iduronate in Heparin-like Trisaccharides. Muñoz-Garcia J.C., Lopez-Prados J., Angulo J., Diaz-Contreras I., Reichardt N., de Paz J.L., Martin-Lomas M. and Nieto P.M.; Chem. Eur. J. 18, 16319-16331 (2012).

    Lectin-Array Blotting: Profiling Protein Glycosylation in Complex Mixtures. Etxebarria J., Calvo J., Martin-Lomas M. and Reichardt N.C; ACS Chem. Biol. 7, 1729-1737 (2012).

    A surface-based mass spectrometry method for screening glycosidase specificity in environmental samples. Beloqui A., Sanchez-Ruiz A.,Martin-Lomas M. and Reichardt N.C.; Chem. Commun. 48, 1701-1703 (2012).

    2011

    Synthesis of 1,3,4,6-tetra-O-acetyl-2-azido-2-deoxy-α,β-D-glucopyranose and 2-azido-4,6-benzylidene-2-deoxy-α,β-D-glucopyranose. Ojeda R. , de Paz J. L., Lucas R., Reichardt N.-C., Liu L. and Martin-Lomas M.; Carbohydrate Chemistry. Proven Synthetic Methods (P. Kovac, Ed.) CRC Press 1, 205-211 (2011).

    Fucosyltransferases as Synthetic Tools: Glycan Array Based Substrate Selection and Core Fucosylation of Synthetic N-Glycans. Serna S., Yan S., Martin-Lomas M., Wilson I.B.H and Reichardt N.C.; J. Am. Chem. Soc. 133, 16495-16502 (2011).

    Experimental observations on the regioselectivity of glycosylation of a 4,6-diol system in the β-D-mannopyranosyl unit of a N-glycan pentasaccharide core structure. Ruiz N., Ferreira S., Padro D., Reichardt N.C., Martín-Lomas M.; Carbohyd. Res. 346, 1581-1591 (2011).

    MALDI-TOF Mass Spectrometric Analysis of Enzyme Activity and Lectin Trapping on an Array of N-Glycans. Sanchez-Ruiz A., Serna S., Ruiz N., Martin-Lomas M., and Reichardt N.C.; Angew. Chem. Int. Ed. 50, 1801-1804 (2011).

    A New Linker for Solid-Phase Synthesis of Heparan Sulfate Precursors by Sequential Assembly of Monosaccharide Building Blocks. Czechura P., Guedes N., Kopitzki S., Vazquez N., Martin-Lomas M. and Reichardt N.C.; Chem. Commun. 47, 8 2390 – 2392 (2011).

    2010

    Construction of N-Glycan Microarrays by Using Modular Synthesis and On-Chip Nanoscale Enzymatic Glycosylation. Serna S., Etxebarria J., Ruiz N., Martin-Lomas M. and Reichardt N.C.; Chem. Eur. J. 16, 13163 – 13175 (2010).

    2009

    Synthesis of a core trisaccharide building block for the assembly of N-glycan neoconjugates. Serna S., Kardak B., Reichardt N.-C. and Martín-Lomas M.; Tetrahedron-Asymmetry 20, 851-856 (2009).